Med Care. 2012 (Dec); 50 (12): 1029–1036 ~ FULL TEXT
Brook I. Martin, PhD MPH, Mary M. Gerkovich, PhD, Richard A. Deyo, MD, MPH,
Karen J. Sherman, PhD, MPH, Daniel C. Cherkin, PhD, Bonnie K. Lind, PhD,
Christine M. Goertz, DC, PhD, and William E. Lafferty, MD
Department of Orthopaedics,
The Geisel School of Medicine at Dartmouth &
Dartmouth-Hitchcock Medical Center,
Lebanon, NH 03756, USA.
This first national study of CAM/chiropractic expenditures for spine conditions finds that neither adds to overall medical spending.
From Page 23: A recent study of 12,036 records in the Medical Expenditure Panel Survey (MEPS) investigated the costs of treating patients with low back and neck pain (Martin et al., 2012). The study estimated the expenditures for care among complementary and alternative medicine (chiropractic, homeopathy, herbalism, acupuncture, and massage) users relative to non-users. This study included a chiropractic-specific analysis of expenditures for chiropractic users versus non-users, as approximately 75% of all complementary and alternative medicine services were rendered by doctors of chiropractic.
Survey data were analyzed for the years 2002–2008. The
analysis demonstrated that seeing a CAM/chiropractic provider did not add to overall medical spending. In fact, adjusted annual healthcare costs among chiropractic users were $424 lower for spine-related costs when compared to non-CAM users.
Additionally, those who used complementary and alternative providers, including doctors of chiropractic, had significantly lower hospitalization expenditures.
BACKGROUND: Health care costs associated with use of complementary and alternative medicine (CAM) by patients with spine problems have not been studied in a national sample.
OBJECTIVES: To estimate the total and spine-specific medical expenditures among CAM and non-CAM users with spine problems.
RESEARCH DESIGN: Analysis of the 2002-2008 Medical Expenditure Panel Survey.
SUBJECTS: Adults (above 17 y) with self-reported neck and back problems who did or did not use CAM services.
MEASURES: Survey-weighted generalized linear regression and propensity matching to examine expenditure differences between CAM users and non-CAM users while controlling for patient, socioeconomic, and health characteristics.
RESULTS: A total of 12,036 respondents with spine problems were included, including 4306 (35.8%) CAM users (40.8% in weighted sample). CAM users had significantly better self-reported health, education, and comorbidity compared with non-CAM users. Adjusted annual medical costs among CAM users was $424 lower (95% confidence interval: $240, $609; P<0.001) for spine-related costs, and $796 lower (95% confidence interval: $121, $1470; P = 0.021) for total health care cost than among non-CAM users. Average expenditure for CAM users, based on propensity matching, was $526 lower for spine-specific costs (P<0.001) and $298 lower for total health costs (P = 0.403). Expenditure differences were primarily due to lower inpatient expenditures among CAM users.
From the FULL TEXT Article:
Complementary and alternative medicine (CAM) includes professional services provided by chiropractic, homeopathic and naturopathic physicians, herbalists, acupuncturists and massage therapists. (Kaptchuk and Eisenberg 2001) As insurance coverage has become more widespread, CAM use among patients with spine problems has increased. (Eisenberg, Davis et al. 1998; Pelletier and Astin 2002; Nahin, Barnes et al. 2009) For example, the number of adults in the United States who sought chiropractic care, the most common type of CAM used by people with spine problems, increased 57% from 1997 to 2006. (Davis, Sirovich et al. 2010)
The financial impact of increased CAM use has been hotly debated. Some have argued that increased use of CAM services reduces the need for more expensive medical care; but others believe that CAM use increases costs because it supplements medical care rather than replacing it. (Metz, Nelson et al. 2004) Concerns that CAM coverage increases health care costs for the general population are not supported by claims data from large insurers or cost-effectiveness studies. (Legorreta, Metz et al. 2004; Sarnat and Winterstein 2004; Haas, Sharma et al. 2005; Nelson, Metz et al. 2005; Grieves, Menke et al. 2009; Liliedahl, Finch et al. 2010; Lind, Lafferty et al. 2010) However, such findings have not been examined using a national sample to estimate the impact of CAM use on total health care costs or for specific types of services (e.g., inpatient, outpatient, prescriptions, and emergency services).
Although a finding of lower expenditures among CAM users with back pain would be consistent with the hypothesis that it obviates the need for more expensive medical care, it might also reflect differences in demographic, clinical and treatment preferences between CAM and non-CAM users. For example, CAM-users are younger, more physically active, less likely to be obese, and have higher educational status and income compared to non-CAM users. (Eisenberg, Davis et al. 1998; Ndetan, Bae et al. 2009) Using data from a nationally representative survey of health care utilization and cost, we estimated differences in the total and spine-specific annual expenditures among CAM and non-CAM users with self-reported spine problems. Two methods (linear regression and propensity score matching) were used to adjust these estimates for observed demographic, clinical, socioeconomic, and health status differences between CAM and non-CAM users.
We examined data from 2002 to 2008 using the Medical Expenditure Panel Survey (MEPS), an annual cross-sectional survey of non-institutionalized U.S. household health care utilization that is supplemented by provider and employer records. (AHRQ 2010) Participants in MEPS are a subsample of participants in the previous year’s National Health Interview Survey. The MEPS data include sampling weights and survey design variables that allow researchers to produce unbiased national estimates of expenditures, utilization and self-reported health status.
We linked unique respondent identifiers in the demographic files to their separate “event” files containing medical encounter details for the following service categories: outpatient care, inpatient care, prescription medication files, and emergency department visits. We performed separate analyses for each type of service category. Many patients have multiple types of events (e.g. both prescription medication and outpatient visits , so these subgroups of service categories are not mutually exclusive.
Average annual national estimates of utilization and expenditures were obtained by dividing the weighting variable by seven, since we combined data from seven years. Figure 1 describes the case selection, the number of survey respondents, as well as the proportion of our sample who were CAM-users.
Weighted and unweighted sample,
We used the International Classification of Disease, 9th revision, Clinical Modification (ICD-9-CM) to identify survey respondents with back and neck problems. We performed this analysis at the Agency for Healthcare Research and Quality’s Data Center in order to have access to fully-specified ICD-9 codes. Publicly available MEPS files are truncated at the 3-digit level to protect respondent confidentiality. Previous studies have used ICD-9-CM codes for capturing spine conditions. (Cherkin, Deyo et al. 1992; Martin, Deyo et al. 2008) Patient-reported medical conditions are translated into ICD-9-CM codes by MEPS survey administrators and provider surveys. We searched all available diagnosis codes for each respondent to identify those who had at least one medical encounter for a back or neck problem. We then identified all inpatient, outpatient, emergency and prescription events for these respondents. We searched all three diagnosis fields for each event record to identify those that were specifically related to a spine problem. The order that diagnosis codes were entered into the diagnosis fields did not matter.
Respondents were grouped into their most severe spinal diagnosis using a mutually-exclusive hierarchy of spinal pathology that we developed with our clinical colleagues. In order of decreasing severity, this hierarchy included codes for scoliosis, spondylolisthesis, stenosis, herniated disc (with or without myelopathy), degeneration (e.g. spondylosis), and spinal sprains or strains.
We excluded patients with non-degenerative spinal pathologies such as spinal fracture, vertebral dislocation, spinal cord injury, inflammatory spondylopathy, myelopathy, osteoporosis, neurological impairment, osteomylitis, or who had post-operative spinal care. We further excluded patients who had cancer, trauma, fractures, drug abuse, HIV or immune deficiencies, or were pregnant. Finally, we limited our analysis to those over age 17.
Classifying CAM users
In 2002, MEPS introduced a new variable to describe 16 types of medical providers. Using this information, we defined a “CAM user” as someone having at least one visit to a doctor of chiropractic, massage therapist, homeopathic provider, acupuncturist, or “other CAM provider” (without further information). Our primary analysis focused on differences between CAM and non-CAM users. “Non-CAM” users were patients who had at least one conventional medical care visit for a spine-related problem (patients who self-reported back pain, but did not have any spine-specific medical visits were excluded). Categorizing a person as a CAM user was based on visits for all reasons, and was not necessarily related to the spine problem. We performed additional analyses focused on expenditure differences between users and non-users of chiropractic care exclusively, while excluding those who used other types of CAM (whether it was in addition to chiropractic care or not), because chiropractic care constituted approximately 75% of all CAM use.
Medical expenditures included all payments made by private insurance, Medicaid, Medicare, patient out-of-pocket costs and other recorded payment sources for office-based or hospital-based outpatient visits, inpatient stays, prescription medications, and emergency department visits. All services incurred during a hospital stay, including direct hospital care, diagnostic tests and procedures, imaging studies, and laboratory work were included as inpatient expenditures. Over-the-counter medications, services provided by free-standing radiology clinics, medical supplies or equipment and dental expenditure were not included in the analysis.
Two costing methods, a direct and an incremental method, were used to estimate expenditures. These methods have different underlying assumptions about how expenditures are related to spine problems. The direct method includes only those costs specifically identified as being spine related (i.e. the event is recorded with a spine-related diagnosis code). The incremental approach includes differences in cost for all care, whether or not they are specifically spine-related (e.g. medical visits for treatment of depression). The difference in mean expenditure between CAM and non-CAM users for all medical care is “attributed” to differences due to CAM use. The incremental method is therefore a more holistic approach that includes potential excesses (or reductions) in expenditures among CAM users whether or not these differences are coded as being spine related. Both methods have been commonly reported in the literature for musculoskeletal and spinal conditions.(AAOS 2008)
Multiple self-reported measures of health and functional status are collected from MEPS respondents. These include: the Short Form-12 Physical Component Summary (PCS) and Mental Component Summary (MCS); perceived physical and mental health (dichotomized as “fair-poor” versus “good-excellent”); any social, work and physical functioning limitations (coded as “any” versus “none”); and needed help for Instrumental Activities of Daily Living (IADL). Specifically, IADL asks respondents whether they need help with tasks such as taking medications, preparing meals, doing laundry, or going shopping. We dichotomized IADL to report the effect of having any limitation on function.
Patient characteristics in MEPS include age, sex, race, ethnicity, education, marital status, US census region, health insurance status, family income, and whether the respondent was unemployed at any time during the year. Health insurance was coded as “Medicare”, “Medicaid”, “Private insurance only”, and “Uninsured”. Family income was defined relative to the federal poverty level (“poor”, “near poor”, “low”, “middle”, “high”). Finally, we used Quan’s version of the Charlson Index to account for comorbidity. (D’Hoore, Bouckaert et al. 1996)
We identified the total number of survey respondents with spine problems, and grouped them based on whether or not they reported any health care utilization delivered by a CAM provider. Differences in the distribution of both patient characteristics and health status measures between CAM and non-CAM users were compared using chi-square comparisons on the weighted data (or by using t-test for age, a continuous variable). Within each service category we examined differences in the overall and spine-specific number of events between CAM and non-CAM users.
We then compared the unadjusted mean annual medical expenditures between CAM and non-CAM users for overall medical care (incremental methods), as well as spine-specific care (direct method). We estimated costs using a generalized linear regression model with a gamma distribution and log link function to account for the skewed nature of cost data. The selection of this distributional family was informed by the Modified Park Test. (Glick HA 2007)
To the unadjusted model we then sequentially added the variables for
1) patient and disease characteristics
(age group, sex, insurance, comorbidity, and spinal diagnosis);
2) socioeconomic factors
(income relative to the federal poverty level, education, work status, and U.S. census region), and
3) self-reported health status
(activity limitation and perceived health).
The fully adjusted model included all potential covariates except when evidence of multicolinearity was found among health measures.
To present the average differences in adjusted costs between CAM and non-CAM users, we weighted each observation using beta-coefficients associated with the corresponding variables from our regression models. This produced the normative cost for each patient based on the experience of patients with similar characteristics. We then reported the difference in these average costs between CAM and non-CAM users.
Because of selection bias concerns, we conducted additional analyses using propensity score matching to estimate differences in costs. Propensity score matching is a non-experimental sampling method that produces a non-CAM group whose distribution on observed covariates is similar to that of CAM users. We calculated a propensity score through an iterative process of balancing the properties among those with the same predicted probability for using CAM, based on the variables that were included in our fully adjusted regression model. (Guo S. 2010) To create this balance, only CAM and non-CAM users whose distributions of the propensity score overlapped were used as a basis for inferences (known as the “region of common support”). Each CAM user was then matched to a single non-CAM user with the most similar propensity score (known as “nearest-neighbor” matching.) Matching on propensity score is more efficient than including a propensity score in a regression model, results in the least amount of selection bias, and is a common approach when test and control groups vary in size. (Austin 2011) The average treatment effect of CAM use on expenditure was then estimated using 1000 bootstrap samples from the matched sample.
All analyses were performed using StataMP, version 11.0 (Stata Corp, College Station, TX) and incorporated weighting and design variables to account for multistage sampling methods. Hypothesis testing was conducted using an alpha level set at 0.05 based on the survey design degree of freedom. The study received a minimal risk approval from the University of Missouri-Kansas City Institutional review board.
Data were analyzed for 12,036 survey respondents for the years 2002 through 2008 who met our criteria, representing an estimated 18.0 million people annually (Figure 1). Of these, 40.8% were CAM users. Chiropractic care was used by 75% of CAM users, followed by 18.8% who used massage, 6.9% using acupuncture, 4.5% for unspecified CAM providers, and 3.4% using homeopathic physicians.
CAM users were significantly younger, and most prevalent in the Midwest and least prevalent in the South. They were more likely to be white, non-Hispanic, privately insured, and employed, while less likely to be widowed, divorced, or separated (Table 1). CAM users also had higher family incomes, less comorbidity, and were more likely to be college-educated compared to non-CAM users.
The majority (60.9%) of patients had spine degenerative conditions, followed by herniated disc (23.8%), sprains and strains (10.7%), scoliosis (2.7%), stenosis (2.5%), and spondylolisthesis (0.4%). Degenerative disc disease and scoliosis were more common diagnoses among CAM than non-CAM users. A diagnosis of disc herniation was less common among CAM users.
Table 2 presents differences in self-reported health status between CAM and non-CAM respondents with spine problems. CAM users reported significantly better levels of perceived physical and mental health, as well as fewer physical, functional, social and disabling limitations. The greatest differences were for physical functioning and perceived health status. For example, 17.8% of CAM users compared to 32.6% of non-CAM users reported physical functioning limitations (p<0.001). Norm-based SF-12 physical and mental component scores were lower (worse) among non-CAM users. These differences in the SF-12 summary scores were statistically significant but not clinically meaningful. Moreover, their scores were not substantially lower than those of the general population.
Among respondents in our study, the mean unadjusted annual medical cost among CAM users was $2,495 (95% CI $1,774 – 3,216) lower than that of non-CAM users (p<0.001) for total health care costs (Table 3), and $685 (95%CI $497 –$872) lower for spine-specific health care services (p<0.001; Table 4). After adjusting for patient characteristics, socioeconomic differences, and health status, the average annual medical cost for all health care was $796 lower (95% CI $121 – $1,470) for CAM users than for non-CAM users (p=0.021), and $424 (95% CI $240 – $609) lower for spine-specific health care services (p<0.001).
Patient characteristics among CAM
and non-CAM users with self-reported spine
problems reported in MEPS 2002–2008.
Health status measures among CAM
and non-CAM users with self-reported spine
problems reported in MEPS 2002–2008.
Average annual per capita total
health costs between CAM and non-CAM
respondents with spine problems,
Average annual per capita spine–
specific health costs among CAM
and non-CAM respondents with spine
problems, MEPS 2002–2008.
Among CAM users, the proportion of outpatient expenditures that were specifically for CAM services was 21.7% (95%CI 20.2, 23.4) for total health care, and 63.5% (95%CI 59.3, 67.8) for spine-specific care.
Differences in both total and spine-specific expenditures were primarily attributed to significantly lower inpatient expenditures among CAM users. After excluding the inpatient service category, we found no difference in total or spine-specific medical expenditures between CAM and non-CAM users.
All but 60 of the 12,036 survey respondents were included in the region of common support (see Methods), and were included in the propensity score matching analyses. In contrast to the regression analysis, the average treatment effect for CAM use on total expenditures was not statistically significant. The total annual expenditures among CAM users were $298 lower than non-CAM users for total care (p = 0.403). However, even with the propensity-matching method, CAM users had significantly lower spine-specific expenditures ($526 lower than non-CAM users; p < 0.001).
Similar patterns of utilization and costs were observed when we considered only patients who did or did not use chiropractic care, while excluding all other types of CAM use from the analysis.
We observed significantly lower overall and spine-specific medical costs among CAM users compared to non-CAM users in a regression model adjusted for patient characteristics, diagnosis, socioeconomic factors, and health status. The lower total costs among CAM users was primarily attributable to their lower expenditures for inpatient services. After excluding inpatient expenditures, there was no difference in spine-specific or overall medical expenditures between CAM and non-CAM users.
As with any non-randomized study, selection bias is a concern when comparing costs of CAM users to non-users. We found that CAM users had significantly better self-reported measures of health status, lower comorbidity, more private insurance, and higher socioeconomic status compared to non-CAM users. These factors are also likely to be related to expenditures. Thus, the observed cost differences associated with CAM use may differ from those that would be observed in a randomized comparison. Indeed, we found that adjusting our analysis for observed differences largely attenuated the cost differences between CAM and non-CAM users. And, by further matching CAM users to non-CAM users who had a similar propensity scores, we found that the magnitude of the effect for CAM use on total health care expenditures was largely attenuated compared to the effects found in the regression models, and that this difference was no longer statistically significant. Nevertheless, even with propensity matching, spine-specific expenditures were significantly lower among CAM users compared to non-users.
A major strength of our study is that it is based on a large and nationally-representative sample, rather than on data from a select clinical study or from a specific health network. However, there are some limitations. Although the use of ICD-9-CM codes is common in spine research, the codes lack specific clinical detail such as disease severity and duration. Even with multiple adjustments for observed group differences, unobserved factors may exist that could explain the remaining differences in costs. It is uncertain whether unmeasured confounding factors could explain the observed difference in costs between CAM and non-CAM users. Finally, differences in healthcare utilization and expenditures between CAM and non-CAM users may be the cause or consequence of differences in health status. Cross-sectional data preclude causal inferences regarding CAM use and health status, but allow us to examine the association of CAM use with expenditures after adjusting for differences in health status. The self-reported health status measures in this study may not reflect baseline values as these data may have been collected either before or after spine-related visits. Future research exploring these differences might benefit from randomized designs or statistical methods (e.g. instrumental variable analysis) that further seek to identify and minimize unmeasured confounding.
Our findings are generally consistent with other studies that have reported that CAM use does not significantly increase overall medical spending. (Haas, Sharma et al. 2005; Nelson, Metz et al. 2005; Grieves, Menke et al. 2009; Lind, Lafferty et al. 2010) Our study is the first to generalize this findings to a nationally representative sample. Whether expanding CAM coverage will retain a budget neutral impact is unclear. On the basis of cost-effectiveness, the UK’s National Institute for Health and Clinical Excellence (NICE) has recommended expanded use of early conservative treatments in response to back pain, and a recent study has shown reduced rates of surgery among those receiving early physical therapy for common acute back pain. (Mayor 2009; Gellhorn, Chan et al. 2010) On the other hand, a Medicare demonstration project recently reported that expanding chiropractic services to include payment for physical examinations, imaging and additional manual services significantly increased costs. (Federal Register 2009) However, concerns exist regard the generalizability of this finding. Costs for all users with neuromuskuloskeletal complaints were significantly higher in demonstration sites when compared to control sites, both before and during the demonstration period. Furthermore, the majority of additional expenditures occurred at one site (Illinois, primarily Chicago and its suburbs). Costs in other demonstration areas either decreased or increased only slightly when compared to control sites.
Our findings are consistent with the hypothesis that, after accounting for clear differences between CAM and non-CAM users, expenditures for CAM users are not higher than those of non-CAM users, and even suggest possible cost savings. Discretionary clinician decisions are the predominant driver of medical spending for back pain; and, despite evidence-based clinical guidelines that recommend conservative treatment approaches, trends suggest increases in the use of advanced imaging, epidural steroid injections, opioid analgesics, and surgical treatments for those with back pain. (Deyo, Mirza et al. 2009) These services are often provided with the expectation that they will obviate the need for more invasive and longer duration therapies. As the health care costs for spine-related pain continue to grow in the absence of evidence of corresponding improvements in population-based outcomes, there is a major need for research that clarifies how the timing, frequency, and effectiveness of CAM services affect subsequent rates of spinal surgery, opioid prescription, epidural steroid injections, and other expensive and invasive treatments for patients with back pain.
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From the Dynamic Chiropractic Article:
Chiropractic Costs: A National Perspective
First national study of CAM / chiropractic expenditures for spine conditions finds neither adds to overall medical spending.
While health care conversations increasingly mention chiropractic care as a viable option for back and neck pain – and research increasingly supports its utility from a clinical standpoint – a recent nationwide study of complementary and alternative medicine (CAM)-related health care expenditures by 12,000-plus adults (ages 17 and older) with spinal conditions lends support to the suggestion that CAM in general, and chiropractic specifically, is also a cost-effective alternative to traditional medical care.
Although CAM users had "significantly better self-reported health, education and comorbidity compared with non-CAM users" – variables critics have relied on in previous studies to explain why CAM users have lower health care expenditures" – the current study revealed that even when controlling for these variables, CAM users had lower annual medical costs ($424 lower) for spine-related conditions and lower total health care costs ($796 lower) than non-CAM users.
According to Brooks, et al., whose findings appear in the December 2012 issue of Medical Care, these cost savings were "primarily due to lower inpatient expenditures among CAM users." However, after controlling for inpatient costs, CAM / chiropractic utilization did not increase spine-specific or overall medical costs above those by non-CAM / chiropractic users. Christine Goertz, DC, PhD, vice chancellor of research and health policy at the Palmer Center for Chiropractic Research and study co-investigator, further illuminated the importance of their findings:
“The extent to which CAM / chiropractic care may or may not increase costs within a health care delivery system is a hotly debated topic. Doctors of chiropractic argue that chiropractic is a substitution for more expensive medical care and thus results in cost savings. Others argue that it adds substantial cost to the system. The small collection of studies that exist to date generally support the argument that chiropractic, at a minimum, does not add cost.”
“However, there are significant weaknesses associated with those studies. For example, many used claims data that was not intended for research purposes and others were restricted to a single delivery system that may not be widely generalizable. Perhaps most importantly is the concern of 'selection bias' (i.e., chiropractic patients tend to be younger, healthier, and have a higher socioeconomic status) setting the groundwork for a legitimate 'chicken or egg' debate. Are chiropractic patients healthier because they went to a DC, or do they go to a DC because they are healthier?”
The Brooks, et al., study is important because:
1) it is the first study that evaluates data from a nationally representative sample of over 12,000 patients with spine-related conditions;
2) investigators were able to control for important socioeconomic and health-related variables; and
3) additional analysis were conducted using a sophisticated statistical technique called propensity scoring, which further addresses the selection bias issue. “Thus, I would consider this paper to be the most definitive work to date on expenditures for patients who seek chiropractic care for back and next problems.”
The study examined data from the Medical Expenditure Panel Survey (MEPS), 2002-2008, relying on ICD-9-CM codes to identify patients with back and neck problems. Included were patients with codes for scoliosis, spondylolisthesis, stenosis, herniated disk (with or without myelopathy), degeneration and spinal strains / sprains. Excluded from consideration were patients with nondegenerative spinal pathologies including spinal fracture, vertebral dislocation, spinal-cord injury, inflammatory spondylopathy, myelopathy, osteoporosis, neurological impairment, osteomylitis or postoperative spinal care. Other exclusionary conditions / scenarios included cancer, trauma, fractures, drug abuse, HIV or immune deficiencies, or pregnancy. All inpatient, outpatient, emergency and prescription events relative to their condition were then identified.
Visits to chiropractic / CAM providers were determined by reviewing the MEPS, which "introduced a new variable to describe 16 types of medical providers" as of 2002. CAM users were patients who had made at least one visit to a doctor of chiropractic, massage therapist, homeopathic practitioner, acupuncturist or "other CAM provider." Non-CAM users were patients who had made at least one visit to a conventional medical practitioner during the same time period. Comprehensive expenditures by patient type (CAM user / non-CAM user) were calculated by reviewing all payment sources for each visit, including private insurance, Medicare / Medicaid, patient out-of-pocket costs and any other recorded payment sources. All cost-generating services performed during outpatient visits, inpatient hospital stays, and ER visits, as well as medication prescriptions, were included in the expenditure total. (OTC medications, services provided by free-standing radiology clinics, medical supplies / equipment, and dental services were not included.)
Of note, the study authors evaluated not only expenditure differences between CAM and non-CAM users, but also between CAM and non-CAM users of chiropractic care exclusively, "excluding those who used other types of CAM (whether it was in addition to chiropractic care or not), because chiropractic care constituted approximately 75% of all CAM use." Similar utilization and expenditure patterns emerged when patients who did / did not use chiropractic care were considered in isolation from use of other CAM types.