Chiro.org - Chiropractic Resource Organization.     Support Chiropractic Research!

Daily Archives: March 3, 2012

Cerebral Perfusion in Patients with Chronic Neck and Upper Back Pain: Preliminary Observations

By |March 3, 2012|Spinal Manipulation, Subluxation|

Cerebral Perfusion in Patients with Chronic Neck and Upper Back Pain: Preliminary Observations

The Chiro.Org Blog


SOURCE:   J Manipulative Physiol Ther. 2012 (Feb); 35 (2): 76-85

Maxim A. Bakhtadze, MD, PhD, Howard Vernon, DC, PhD, Anatoliy V. Karalkin, MD, PhD, Sergey P. Pasha, MD, PhD, Igor O. Tomashevskiy, MD, PhD, David Soave, MS

Center for Manual Therapy, Moscow, Russia.


OBJECTIVE:   The purpose of this study was to determine the correlation between cerebral perfusion levels, Neck Disability Index (NDI) scores, and spinal joint fixations in patients with neck pain.

METHODS:   Forty-five adult patients (29 were female) with chronic neck/upper thoracic pain during exacerbation were studied. The subjects were grouped according to NDI scores: mild, moderate, and severe. The number of painful/blocked segments in the cervical and upper thoracic spine and costovertebral joints, pain intensity using the visual analog scale, and regional cerebral blood flow of the brain using single-photon emission computed tomography (SPECT) were obtained. The SPECT was analyzed semi-quantitatively. Analysis of variance tests were conducted on total SPECT scores in each of the NDI groups (P < .05). Univariate correlations were obtained between blockage, pain, and SPECT scores, as well as age and duration. A multivariate analysis was then conducted.

RESULTS:   Group 1 (mild) consisted of 14 patients. Cerebral perfusion measured by SPECT was normal in all 8 brain regions.

Group 2 (moderate) consisted of 16 patients. In this group, a decrease in cerebral perfusion was observed (range, 20%-35%), predominantly in the parietal and frontal zones. (more…)