The Consequences of Zinc Deficiency
SOURCE: Dynamic Chiropractic
By James P. Meschino, DC, MS
A study published in the Journal of Nutritional Biochemistry  underscores the importance of zinc supplementation, especially as we get older, as an important means to help prevent cancer, support immune function, and control inflammation associated with many health problems, including cancer, heart disease, autoimmune disease and diabetes.
Previous studies by the same researchers showed that, in both animal and human studies, zinc deficiency can cause DNA damage linked to cancer risk. The latest study suggests that zinc deficiency also leads to systemic inflammation. In addition, immune system cells are also particularly vulnerable to zinc deficiencies, and zinc is essential to protect against oxidative stress and help repair DNA damage.The Latest Findings
Based on findings with laboratory animals, the researchers found that the mechanisms to transport zinc are disrupted by age-related epigenetic changes, which can cause an increase in DNA methylation and histone modifications related to cancer development. More specifically, zinc transporters were significantly dysregulated in old animals. They showed signs of zinc deficiency and had an enhanced inflammatory response, even though their diet supposedly contained adequate amounts of zinc.
When the animals were given about 10 times their dietary requirement for zinc, the biomarkers of inflammation were restored to those of young animals.Why You Should Supplement With Zinc