Chiro.org - Chiropractic Resource Organization.     Support Chiropractic Research!

Daily Archives: January 21, 2014

The Efficacy of Spinal Manipulation, Amitriptyline and the Combination of Both Therapies for the Prophylaxis of Migraine Headache

By |January 21, 2014|Chiropractic Care, Evidence-based Medicine, Headache, Migraine|

The Efficacy of Spinal Manipulation, Amitriptyline and the Combination of Both Therapies for the Prophylaxis of Migraine Headache

The Chiro.Org Blog


SOURCE:   J Manipulative Physiol Ther 1998 (Oct);   21 (8):   511–519

Nelson CF, Bronfort G, Evans R, Boline P,
Goldsmith C, Anderson AV

Center for Clinical Studies,
Northwestern College of Chiropractic,
Bloomington, MN 55431, USA.


BACKGROUND:   Migraine headache affects approximately 11 million adults in the United States. Spinal manipulation is a common alternative therapy for headaches, but its efficacy compared with standard medical therapies is unknown.

OBJECTIVE:   To measure the relative efficacy of amitriptyline, spinal manipulation and the combination of both therapies for the prophylaxis of migraine headache.

DESIGN:   A prospective, randomized, parallel-group comparison. After a 4-wk baseline period, patients were randomly assigned to 8 wk of treatment, after which there was a 4-wk follow-up period.

SETTING:   Chiropractic college outpatient clinic.

PARTICIPANTS:   A total of 218 patients with the diagnosis of migraine headache.

INTERVENTIONS:   An 8-wk course of therapy with spinal manipulation, amitriptyline or a combination of the two treatments.

MAIN OUTCOME MEASURES:   A headache index score derived from a daily headache pain diary during the last 4 wk of treatment and during the 4-wk follow-up period.

There are more articles like this @ our:

Headache and Chiropractic Page

(more…)