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Newer antimicrobial therapies proposed may lead to resistance of human innate immune response.

But like antibiotics, bacteria can evolve resistance to AMPs, risking the possibility that bacteria will also be able to resist the first arm of the human immune system. […]

The Facts About Fevers

Chiro.Org Blog: Our body’s first line of defense when invaded by any microbe, virus or bacteria is cells called microphages; a strong, healthy immune system may be able to eliminate the problem with this first step alone. If these fail to contain the microbe/”bug,” then the body creates other pryogens and proteins to try to assist. Once these have been created, the hypothalamus in the brain recognizes there is an invader and raises the body temperature to assist in killing it off. […]