Strokes May Seem Rare, But Can Occur 230% More Often Using The Pill
SOURCE: MedPage Today ~ June 13, 2012
By Todd Neale, Senior Staff Writer
A large Danish registry study found that the risks of thrombotic stroke or myocardial infarction (MI) roughly doubled in women taking oral contraceptives with low-to-moderate doses of ethinyl estradiol.
Note that the overall number of thrombotic strokes or MIs was small.
The relative risks of thrombotic stroke and myocardial infarction (MI) are higher among users of hormonal contraception, although absolute risks remain low, a Danish study showed.
Use of oral contraceptives combining low-to-moderate doses of ethinyl estradiol and various progestins was associated with up to 2.3 times the risks of thrombotic stroke or MI compared with non-use, according to Øjvind Lidegaard, DrMedSci, of Copenhagen University Hospital, and colleagues.
The type of progestin in the pill had little effect on the risks, the researchers reported in the June 14 issue of the New England Journal of Medicine.
To put the risk in perspective, they estimated that among 10,000 women taking a pill combining desogestrel with ethinyl estradiol at a dose of 20 μg for 1 year, two will have arterial thrombosis and seven will have venous thrombosis.