PMC full text:
Published online 2018 Oct 15. doi: 10.1136/bmjopen-2017-020222
Table 5
Comparator | Quality | Population size | Complementary medicine | Safety | Cost-effectiveness |
Active intervention | Good | Medium | Manual therapy87* | Some evidence of potential harm82 83† | Some evidence of CE87 88‡ |
Moderate | Large | Manipulation82§¶ | Some evidence of potential harm82 83† | Some evidence of CE87 88‡ | |
Moderate | Small | Manual therapy88** | Some evidence of potential harm82 83† | Some evidence of CE87 88‡ | |
Placebo | Moderate | Medium | Acupuncture89 | Some evidence of safety89 | No data40 |
Usual care | Moderate | Medium | Acupuncture89 | Some evidence of safety89 | No data40 |
*Manual therapy plus exercise compared with exercise alone.
†Reduced cost of therapy.
‡Minor adverse events and rare but devastating adverse effects from manipulation.
§Compared to medication.
¶Also showed effectiveness for pain compared with any control.
**Mobilisation, manipulation and soft tissue techniques.
CE, cost effectiveness.