PLoS One 2025 (Jan 28); 20 (1): e0317663

Fig 2. Incidence of opioid-related adverse events (ORADEs) after propensity matching.

Incidence in the chiropractic spinal manipulation (CSM) cohort (blue) is lower than that of the usual medical care cohort (orange). The 95% confidence intervals do not overlap, suggesting a meaningful difference between cohorts.