J Can Chiropr Assoc 2026 (Apr); 70 (1): 27-54
Appendix 7. Certainty of evidence for intervention --
Efficacy of SMT parameters for Low back pain
Outcomes No. of participants randomized (Studies) Parameter Results favor (SMT, null, parameter) Risk of Bias (low, acceptable, high) Certainty of the evidence Comments (Reasons for downgrade/ upgrade) Pain Intensity
Scale: NPRS, 11-Point box pain scale49 (1 RCT) Thrust SMT vs Non-thrust SMT 1 favors null 1 acceptable risk ⊕○○○
Very LowImprecision Risk of bias 182 (1 RCTs) 12 weeks SMT vs 36 weeks SMT 1 favors null 1 low risk ⊕⊕○○
LowImprecision Back-Specific Disability Status
Scale: ODI49 (1 RCT) Thrust SMT vs Non-thrust SMT 1 favors null 1 acceptable risk ⊕○○○
Very LowImprecision Risk of bias 182 (1 RCTs) 12 weeks SMT vs 36 weeks SMT 1 favors null 1 low risk ⊕⊕○○○
LowImprecision Functional Status
Scale: SPPB182 (1 RCTs) 12 weeks SMT vs 36 weeks SMT 1 favors 36 weeks 1 low risk ⊕⊕○○
LowImprecision Quality of Life/ Activities of daily living
Scale: EQ182 (1 RCTs) 12 weeks SMT vs 36 weeks SMT 1 favors null 1 low risk ⊕⊕○○
LowImprecision Abbreviations:
NPRS = numerical pain rating scale;
ODI = Oswestry Disability Index;
RCT = randomized controlled trial;
SMT = spinal manipulative therapy;
SPPB = Short Physical Performance Battery;
EQ = EuroQol EQ-5D