From The January 2001 Issue of Nutrition Science News
The carotenoids lutein and zeaxanthin, found in foods such as kale and spinach and not synthesized by the body, protect against macular degeneration. A new two-part study by researchers at Florida International University in Miami found higher dietary intake of these carotenoids resulted in higher serum concentrations, which resulted in greater macular pigment, a retina protectant. Researchers first measured diet and serum carotenoids of 19 men and women between age 18 and 60. Using photometry, they determined the optical density of their macular pigments. There was a direct correlation between dietary intake of lutein and zeaxanthin and the density of the macular pigments.
Researchers then took serum and eye samples from 23 deceased individuals who had donated their organs to science. Serum levels of lutein and zeaxanthin correlated with the amount of these two carotenoids in the retinas. Eyes with macular degeneration contained lower levels of lutein and zeaxanthin. The researchers conclude that their study "forges a link" between a variety of research studies on these carotenoids and macular degeneration, strengthening the hypothesis that low levels of lutein and zeaxanthin directly cause age-related macular degeneration.
Experimental Eye Research 2000 (Sep); 71 (3);239-245