| Amitryptyline | 100–150 mg/day | 6 to 8 | Dry mouth, sedation, dizziness, confusion, arrhythmias, orthostatic hypotension, constipation, urinary retention, blurred vision, weight gain |
| Nortriptyline | 100–150 mg/day | 6 | Dry mouth, sedation, dizziness, confusion, orthostatic hypotension, constipation, urinary retention, blurred vision, weight gain, arrhythmias |
| Implipramine | 5150 mg/day | 4 | Dry mouth, sedation, dizziness, confusion, orthostatic hypotension, constipation, urinary retention, blurred vision, weight gain, arrhythmias |
| Desipramine | 200–250 mg/day | 6 | Dry mouth, sedation, confusion, orthostatic hypotension, constipation, urinary retention, blurred vision, weight gain, arrhythmias, dizziness |
| Venlafaxine | 150–225 mg/day | 4 to 6 | Headache, nausea, sedation, constipation, dizziness, dry mouth, sexual dysfunction, hypertension, seizures, diarrhoea |
| Duloxetine | 600–120 mg/day | 4 | Nausea, somnolence, dizziness, dry mouth, constipation, sweating, weakness, headache, diarrhoea |
