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Published online 2007 Oct 24. doi:  10.1186/1475-2891-6-30

Table 5

Risk of suboptimal or elevated serum biomarker concentrations and elevated blood pressure by supplement user group.

OutcomeCases: n/(%)OR*95% CI*
Homocysteine (>9 μmol/L)
 Multiple Supp users30/(10.9)0.110.06–0.19
 Single Supp users69/(37.0)0.530.34–0.83
 No Supp users282/(45.3)1.00

C-reactive protein (>0.3 mg/dL)
 Multiple Supp users0/(0.00)
 Single Supp users51/(30.6)0.660.40–1.09
 No Supp users230/(41.3)1.00

Total cholesterol (>200 mg/dL)
 Multiple Supp users145/(52.5)0.780.56–1.09
 Single Supp users89/(57.8)1.080.72–1.62
 No Supp users291/(54.3)1.00

HDL-cholesterol (<40 mg/dL males, <50 mg/dL females)
 Multiple Supp users44/(15.8)0.500.33–0.75
 Single Supp users40/(24.5)0.580.41–0.83
 No Supp users203/(38.0)1.00

Ratio total cholesterol to HDL-cholesterol (<5)
 Multiple Supp users35/(12.7)0.490.32–0.74
 Single Supp users48/(35.3)1.050.64–1.73
 No Supp users189/(36.5)1.00

Triglycerides (≥150 mg/dL)
 Multiple Supp users52/(18.8)0.440.27–0.71
 Single Supp users31/(41.5)0.990.50–1.94
 No Supp users157/(42.8)1.00

LDL-cholesterol (>130 mg/dL)
 Multiple Supp users109/(39.5)0.960.56–1.65
 Single Supp users32/(47.6)1.190.70–2.03
 No Supp users101/(42.7)1.00

Blood Pressure (DBP>80 mmHg or SBP>120 mmHg)
 Multiple Supp users154/(55.6)0.610.41–0.92
 Single Supp users117/(71.2)1.340.88–2.03
 No Supp users353/(64.6)1.00

* Logistic regression methods were used to estimate odds ratios (OR) with 95% confidence intervals (CI), adjusted as in footnote to Table 4. The referent group for risk estimation was the No Supp group.

OR and 95% CI not estimable because zero events in the user group. Number and percent shown instead.

HDL = high-density lipoprotein, LDL = low-density lipoprotein, DBP = diastolic blood pressure, SBP = systolic blood pressure.

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