The Role of n-3 Polyunsaturated Fatty Acids in the Prevention and Treatment of Breast Cancer

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Published online 2014 Nov 18. doi: 10.3390/nu6115184

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Table 8

Individual effect of ALA, EPA and DHA on different types of BC.

BC Cell Type	ALA	EPA	DHA
MDA-MB-231 (ER−)	✓	✓	✓
MDA-MB 435 (ER−)	NA	✓	✓
MCF-10A (ER−)	—	✓	✓
HBL-100 (ER−)	✓	✓	✓
MCF-7 (ER+)	—	✓	✓
ZR-75 (ER+)	—	✓	✓
T-47-D (ER+)	—	✓	✓
SK-Br3 and BT-474 (HER-2/neu positive)	✓	NA	✓

✓ have significant inhibitory effect on cell proliferation; — slightly inhibit the cell growth; NA: not available.