| 1–6 months of age (seen less frequently 7–12 months of age) | Patient was 3 months of age |
| Gender: male predominant (60:40) | Female gender |
| Paroxysmal fuss, cry patterns which are not easily consoled | The patient’s crying described as not easily consoled. |
| High intensity, piercing cries are common | Cries are described as high-pitched sounds. |
| Crying peaks in evenings, but may occur throughout the day. | Crying occurs throughout the day, particularly after feeding |
| Many episodes of crying as well as long bouts of crying | Many episodes and long bouts of crying |
| Feeding patterns: breast, formula or mixed | Feeding difficulties: the patient was unable to make a complete seal |
| Feeding problems common | Feeding difficulties: the patient was unable to make a complete seal |
| “Pained faces” (facial grimaces) accompany crying | Facial grimacing accompany crying |
| Body unrest, flailing limbs, raised knees, clenched fists, arching postures, general irritability | Body unrest described as “wiggling” during sleep and general irritability. The patient demonstrated arching posture. |
| Sleep disorders common (difficulty falling asleep and staying asleep) | Difficulty falling asleep and staying asleep. |
