
| PMC full text: | Published online 2011 Dec 6.   doi:  10.1016/j.echu.2011.07.001 
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Table 1
Characteristics and results of included studies
| Author | Study type | Study population | Interventions | Outcomes | Results | 
|---|---|---|---|---|---|
| Moller et al4 | Survey | Danish DCs | Maint care for the LBP patient | Types of maintenance care | Similar strategies to DCs in different countries | 
| Jamison9 | Survey | American & Australian DCs | Maint care | Definitions of maintenance care | Purpose, components, conditions, and perceptions defined | 
| Rupert10 | Survey | American DCs | Maint care | Attitudes & practice patterns | Purpose, components, conditions, perceptions, income are defined | 
| Rupert et al11 | Survey | American chiropractic patients >65 y old | Maint care | 5-y history of maint care | Types of care are defined | 
| Axen et al37 | Survey | Swedish DCs | Maint care for LBP patient | Consensus of clinical reasoning | Maint care is provided to prevent relapses. Past freq of episodes is important in making recommendations. 50% improvement needed to recommend tertiary maint care. | 
| Hansen et al14 | Survey | Danish DCs | Maint care for LBP patient | Indications of maint care | Hx of LBP with a prior response to care is indication for maint care | 
| Sandnes et al15 | Clinical observations | 868 patients from 15 Danish and 13 Norwegian chiropractors | Chiropractic care | Frequency of maint care | 2-wk to 3-mo intervals | 
| Senna and Machaly17 | Single blinded placebo controlled | Chronic nonspecific LBP patient | Spinal manipulation | Pain, disability, patient satisfaction, health status | Improved pain & disability with MMT | 
| Hawk et al18 | Randomized pilot | Patients >65 y old | Spinal and extravertebral manipulation | Balance, chronic pain, dizziness | Improved dizziness, pain & disability with extended care | 
| Burton and Tillotson19 | Observational | LBP patients <40 y old | Measurement of sagittal lumbar mobility | Prevalence | Reduced mobility in middle-aged patients with sciatica | 
| Burton et al20 | Observational | 958 LBP patients | Measurement of sagittal lumbar mobility | Prevalence | Mobility changes in current and past LBP patients | 
| Cramer et al21 (1) | Laboratory | 87 Rats | Spinal fixation | Degeneration | Time-dependent degenerative changes | 
| Cramer et al22 (2) | RCT | 64 Healthy students | Side posture manipulation | Spinal joint response | Gapping of the Z-joint | 
| Cramer et al23 (3) | Laboratory | 23 Rats | Spinal fixation | Joint adhesions | Time of onset of joint adhesions | 
| Cramer et al24 (4) | RCT | 16 Healthy students | Side posture manipulation | MRI measurement of joint gapping | Gapping of the Z-joint found with manipulat | 
| He and Dishman26 | Laboratory | 32 Guinea pigs | Knee fixation | Electron microscopy | Spinal motor neuronal degeneration | 
| Kader et al27 | Retrospective | 78 Low back & leg pain pts | MRI | Multifidus atrophy | + Correlation of atrophy with low back and leg pain | 
| Fahim28 | Laboratory | Rats | Immobilization of ankle & knees to fixate soleus | Light microscope | Degeneration of nerve terminals and reversal with remobilization | 
| Lundbye-Jensen and Nielsen29 (1) | Observational | 12 Healthy humans | Immobilization of foot & ankle | H-reflex & muscle torque | Disuse caused plastic changes in interneuronal circuitry with reversal noted with remobilization | 
| Lundbye-Jensen and Nielsen30 (2) | Observational | 10 Healthy humans | 1-wk immobilization of wrist & hand | H-reflex & muscle torque | Spinal and central neuroplastic changes | 
| Brenner et al32 | Case report | 1 Low back and thigh pain pt | Spinal manipulation and diagnostic ultrasound imaging | Multifidus activation with lift task | Increased muscle activation post-SMT and 1-d post-tx | 
| Pickar33 | Literature review | N/A | Spinal manipulation | Neurophysiological effects of SMT | SMT impacts primary afferent neurons, the motor system, & pain. | 
| Descarreaux et al36 | RCT | 30 Nonspecific LBP patients | Spinal manipulation | Pain & disability | MMT may be beneficial to maintain post acute treatment pain, disability levels |