| PMC full text: | Published online 2013 Jul 25. doi: 10.1093/scan/nst079
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Table 1
Return to: Neurobiology of Placebo Effects: Expectations or Learning?
Effects of Expectation (Expect.) − Effectiveness (Effect.) comparisons on MPQ and VAS score changes after placebo administration
| High Expect/ Low Effect (1) | Low Expect/ Low Effect (2) | High Expect/High Effect(3) | Low Expect/High Effect(4) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| mean (s.d) | mean (s.d) | mean (s.d) | mean (s.d) | F | Sig. | Post hoca | Mean diff. (s.e.) | Sig. | ||
| Number of subject | 7 | 19 | 13 | 9 | ||||||
| Expectations | 75.7 ± 14 | 24.2 ± 14.2 | 76.15 ± 13.1 | 43 ± 11.3 | 48.6 | <0.001 | 4 > 1 | −30.2 ± 6.7 | <0.001 | |
| 4 > 2 | 20.2 ± 5.4 | 0.003 | ||||||||
| 4 > 3 | −31.7 ± 5.8 | <0.001 | ||||||||
| 3 > 2 | 51.9 ± 4.8 | <0.001 | ||||||||
| 2 > 1 | −51.5 ± 5.9 | <0.001 | ||||||||
| Subjective effectiveness | 18.5 ± 12.5 | 19.15 ± 14.57 | 75 ± 14.9 | 71.1 ± 11.4 | 61.4 | <0.001 | 4 > 1 | 52.5 ± 6.9 | <0.001 | |
| 4 > 2 | 51.9 ± 6 | |||||||||
| 3 > 1 | 56.4 ± 6.5 | |||||||||
| 3 > 2 | 55.8 ± 5 | |||||||||
| Δ MPQ after placebo | −5.5 ± 10 | −0.4 ± 5.6 | 3.3 ± 8 | 10 ± 7.4 | 6.7 | 0.001 | 4 > 1 | 15.5 ± 3.7 | 0.001 | |
| 4 > 2 | 10.3 ± 3 | 0.007 | ||||||||
| Δ VAS after placebo (0–20 min) | −9 ± 14 | 0 ± 9.6 | 11 ± 11 | 22 ± 10 | 14.3 | <0.001 | 4 > 1 | 31 ± 5 | <0.001 | |
| 4 > 2 | 22 ± 4.4 | <0.001 | ||||||||
| 3 > 1 | 21.1 ± 5.1 | 0.001 | ||||||||
| 3 > 2 | 11.7 ± 4 | 0.028 | ||||||||