Different Placebos, Different Mechanisms, Different Outcomes: Lessons for Clinical Trials

doi:10.1371/journal.pone.0140967

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PLoS One. 2015; 10(11): e0140967.

Published online 2015 Nov 4. doi: 10.1371/journal.pone.0140967

Copyright/LicenseRequest permission to reuse: Copyright © 2015 Benedetti, Dogue
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Experimental design.

The sequence of test sessions is shown for all groups, starting from 8:00 AM of Day 1 at sea level to 8:00 PM of Day 3 at 3500 m.

Vmin = minute ventilation;
PG = prostaglandins;
TX = thromboxane.