Different Placebos, Different Mechanisms, Different Outcomes: Lessons for Clinical Trials

doi:10.1371/journal.pone.0140967

PMC full text:

PLoS One. 2015; 10(11): e0140967.

Published online 2015 Nov 4. doi: 10.1371/journal.pone.0140967

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5

Means (+SD) for all the measurements in the aspirin group.

After aspirin administration for three consecutive sessions, real aspirin was replaced with placebo aspirin. Note that placebo mimicked the effects of real aspirin for headache pain, PGE2, PGD2, PGF2, PGI2, TXA2, but it had no effect on SO2, Vmin, pH. *P<0.01; **P<0.05.