Neural Correlates of Fear of Movement in Patients with Chronic Low Back Pain vs. Pain-Free Individuals

doi:10.3389/fnhum.2016.00386

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Front Hum Neurosci. 2016; 10: 386.

Published online 2016 Jul 26. doi: 10.3389/fnhum.2016.00386

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Figure 2

Results of the voxel-wise regression analysis. (A) Positive correlations between the Tampa Scale of Kinesiophobia (TSK) score and brain activity based on the contrast “harmful movements > neutral movements” (p < 0.05, cluster-level FWE-corrected). Left angular gyrus, left insula, left orbitofrontal cortex (OFC), right caudate, left amygdala, left postcentral gyrus/precuneus. (B) Significant group difference as a function of the TSK score in the left dorsal amygdala (Interaction 0 0 1 −1; p < 0.001, uncorrected).