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Table 5

Summary of the risk of bias in RCT, non randomised controlled trials and controlled before-after studies

Risk of bias category1234567891011121314
Was the allocation sequence adequately generated?ULLLLLLLLULHUH
Was the allocation adequately concealed?LLLLLLULLUUHUU
Were baseline outcome measurements similar?LUULULHLLHHLHH
Were baseline characteristics similar?LUULLLLLLHHLHL
Were incomplete outcome data adequately addressed?LLLLHHLHHLUHHH
Was knowledge of the allocated intervention adequately prevented during study?LLLHLUULLLUUUU
Was the study adequately protected against contamination?LLLLLLLLLLLLLU
Was the study free from selective outcome reporting?LLLLLLLLLLLLLL
Was the study free from other risk of bias?LLLLLLLHHLLLLL
Abbreviations: 1 – Winkens et al., [47]; 2 – Eccles et al., [24]; 3 – Kerry et al., [22]; 4 – Dey et al., [29]; 5 – Bekkering et al., [26]; 6 – Engers et al., [46]; 7 - Bishop & Wing, [28]; 8 – Bekkering et al., [45]; 9 – Engers et al., [27]; 10 – Stevenson et al., [30]; 11 - Schectman et al., [23]; 12 – McGuirk et al., [32]; 13- Becker et al., [44]; 14 – Goldberg et al., [31]; H – High risk of bias; L – Low risk of bias; U – Unclear risk of bias