a. Production of sTNFR2 in the studied subjects was induced by 48 h stimulation of WB cultures with the combination of LPS and PHA (1 μ/ml and 10 μg/ml, respectively). Baseline levels of sTNFR2 were significantly increased (P = 0.0001–0.001) in patients with chronic LBP, when compared with both asymptomatic subjects and patients with acute LBP (19), and were not altered post-SMT. b. Production of IL-10 in asymptomatic control subjects and LBP patients was induced by 48 h stimulation of WB preparations with the combination of LPS and PHA (1 μ/ml and 10 μg/ml, respectively). Compared with the control group, the production of IL-10 was significantly reduced at baseline (19) and was not changed following SMT treatments in patients with acute (as well as chronic LBP patients (P = 0.03 and P = 0.01, respectively)
