Logo of ecamEvidence-based Complementary and Alternative Medicine : eCAM
PMC full text:

Table 3

Summary of findings of acupuncture for neck pain (only pain and functional outcomes).

Duration and cause of painOutcomesGRADE*Findings
Acupuncture versus no treatment

Acute/subacute, chronic, and mixed, (specific, nonspecific)NA Insufficient
No trial
NA

Unknown specificPain intensity score (SF-MPQ) Low
Design: RCT
ROB: Medium
Consistency: NA (only 1 trial)
Directness: yes
In one trial [75], acupuncture was significantly better than no treatment in reducing pain intensity short-term after the end of treatment (mean change: −15.2 ± 13.3 versus −5.3 ± 8.7, P = 0.043).

Unknown nonspecificNA Insufficient
No trial
NA

Acupuncture versus placebo

Acute/subacute specific, nonspecificNA Insufficient
No trial
NA

Chronic specificPain intensity score (VAS) Moderate
Design: RCT
ROB: Medium
Consistency: yes
Directness: yes
Precision: yes
In three trials, acupuncture [77, 209] or dry needling [78] was similar to sham acupuncture [77] or laser acupuncture [78, 209] immediately or at short term after the treatment. In one of these trials [78], posttreatment mean VAS values in dry needling and sham laser acupuncture groups were 29.2 (±21.9) and 28.0 (±19.4), respectively.
The meta-analysis of two trials indicated no significant difference between acupuncture and placebo immediately after the end of treatment (pooled mean difference: 0.27, 95% CI: −0.60, 1.13) [79]. See Figure 6.
NDI score Low
Design: RCT
ROB: Medium
Consistency: NA (only 1 trial)
Directness: yes
In one trial [77], the mean disability score was not significantly different between acupuncture and sham-acupuncture groups immediately posttreatment (5.5 ± 4.5 versus 6.2 ± 3.1, P = 0.52).

Chronic nonspecificPain intensity score (VAS) Low
Design: RCT
ROB: Medium
Consistency: no
Directness: yes
Precision: yes
The meta-analysis of three trials showed no significant difference between acupuncture and sham-acupuncture immediately posttreatment (pooled mean difference: −0.24, 95% CI: −1.20, 0.73) [8082] (See Figure 6). Trials comparing acupuncture to other types of placebos (e.g., TENS, drug) [83, 8587, 210] could not be pooled due to heterogeneity across outcomes, followup periods, or missing data.
NDI score Moderate
Design: RCT
ROB: Low
Consistency: NA (only 1 trial)
Directness: yes
In one trial [83, 210], intermediate posttreatment mean disability was significantly reduced in acupuncture compared to placebo group (8.89 ± 6.57 versus 10.72 ± 9.11, P < 0.05).

Mixed specificPain intensity score (VAS) Low
Design: RCT
ROB: High
Consistency: NA (only 1 trial)
Directness: yes
In one trial [88], there was no significant difference between acupuncture and placebo (laser pen) at intermediate-term posttreatment followup (2.59 ± 2.18 versus 2.89 ± 2.63, P > 0.05).

Mixed nonspecificNA Insufficient
No trial
NA

Unknown specificNo pain or disability outcome reportedNAOne trial [27] reporting % subjects without symptoms.

Unknown nonspecificNA Insufficient
No trial
NA

Acupuncture versus pain medication

Acute/subacute, mixed (specific, nonspecific)NA Insufficient
No trial
NA

Chronic specificPain intensity score (VAS, SF-MPQ) Low
Design: RCT
ROB: High
Consistency: no
Directness: yes
Of the three trials [8991] comparing acupuncture to medications, in two [89, 90] there was no significant difference between acupuncture and injection of lidocaine [89, 90], lidocaine plus corticoid [90], or botulinum toxin [90] at short-term posttreatment followup. In one of the trials [89], two-week posttreatment mean VAS values were 3.82 ± 2.47 for acupuncture and 3.46 ± 2.47 for lidocaine (P > 0.05). In another trial [91], acupuncture was better than NSAIDs immediately after treatment (mean VAS score: 1.87 ± 1.90 versus 4.76 ± 2.05, P < 0.05).

Chronic nonspecificPain intensity score (VAS) Low
Design: RCT
ROB: High
Consistency: yes
Directness: yes
None of three trials comparing acupuncture to medication (e.g., NSAIDs, analgesics) demonstrated significant between-group differences [69, 70, 87]. In one of the trials [69], acupuncture had a better mean score versus pain medication group at immediate (mean VAS score: 4.0 ± 4.4 versus 6.0 ± 4.4) or at intermediate-term followup (mean VAS score: 2.5 versus 4.7) [69, 72].

Unknown specificPain intensity score (VAS, SF-MPQ) Low
Design: RCT
ROB: High
Consistency: yes
Directness: yes
In two trials [28, 92], acupuncture was significantly more effective than injection of lidocaine in the short-term. In one trial [28], the mean pain scores were 5.71 ± 2.49 versus 6.91 ± 3.22 (P < 0.05).

Unknown nonspecificNA Insufficient
No trial
NA

Acupuncture versus physiotherapy

Acute/subacute, chronic, mixed, or unknown (specific, nonspecific)NA Insufficient
No trial
NA

Acupuncture versus mobilization

Acute/subacute, mixed, or unknown (specific, nonspecific)NA Insufficient
No trial
NA

Chronic specificNA Insufficient
No trial
NA

Chronic nonspecificPain intensity score (VAS) Low
Design: RCT
ROB: Medium
Consistency: NA (only 1 trial)
Directness: yes
In one trial [93], there was no significant difference between acupuncture and standard localized mobilization techniques at short- or intermediate-term posttreatment followup (no numerical data on mean scores were reported).
Disability (NPQ score) Low
Design: RCT
ROB: Medium
Consistency: NA (only 1 trial)
Directness: yes
In one trial [93], there was no significant difference between acupuncture and standard localized mobilization techniques at short- or intermediate-term posttreatment followup (no numerical data on mean scores were reported).

Acupuncture versus usual care

Acute/subacute, mixed, or unknown (specific, nonspecific)NA Insufficient
No trial
NA

Chronic specificNA Insufficient
No trial
NA

Chronic nonspecificDisability (NPQ score) Low
Design: RCT
ROB: Medium
Consistency: NA (only 1 trial)
Directness: yes
In one trial [94], acupuncture was added to general practice care and showed no difference in disability (NPQ) compared to general practice care alone immediately posttreatment (22.73 ± 18.64 versus 25.72 ± 16.29, P > 0.05).

Acupuncture versus manipulation

Acute/subacute, mixed, or unknown (specific, nonspecific)NA Insufficient
No trial
NA

Chronic specificPain intensity score (VAS) Low
Design: RCT
ROB: High
Consistency: NA (only 1 trial)
Directness: yes
In one trial [24], there was no significant difference between acupuncture and spinal manipulation at short-term followup (mean VAS: 4.46 ± 3.11 versus 4.43 ± 2.51).

Chronic nonspecificPain intensity score (mean % VAS) Low
Design: RCT
ROB: High
Consistency: no
Directness: yes
In one trial [69], acupuncture was better than manipulation in reducing pain intensity at short-term followup (50.0% versus 42.0%).
In another trial [70], immediate posttreatment reduction in pain intensity was significantly greater in manipulation (VAS: 33.0%) versus acupuncture (VAS score % reduction not reported).
Pain intensity score (VAS) Low
Design: RCT
ROB: High
Consistency: NA (only 1 trial)
Directness: yes
In one trial [69, 72], median pain intensity scores in the acupuncture and manipulation groups did not differ at intermediate-term followup (VAS median scores: 2.5 versus 2.8, P = NR).
Disability score (NDI) Low
Design: RCT
ROB: High
Consistency: yes
Directness: yes
Two trials demonstrated significant superiority of manipulation over acupuncture in improving neck disability.
In the first trial [70], median NDI score reduction in neck disability immediately posttreatment was significantly greater in manipulation (−10.0, 95% CI: −14.0, −4.0) than acupuncture group (−6.0, 95% CI: −16.0, 2.0).
In the second trial [69], the posttreatment NDI values were significantly more improved in manipulation (median: 22; range: 2–44) than acupuncture group (median: 30; range: 16–47); P value not reported.

Acupuncture versus massage

Acute/subacute, mixed, or unknown (specific, nonspecific)NA Insufficient
No trial
NA

Chronic specificPain intensity score (VAS) Low
Design: RCT
ROB: High
Consistency: NA (only 1 trial)
Directness: yes
In one trial [209], acupuncture was significantly better (VAS score scale: 0–100) compared to massage in a short-term posttreatment followup (mean VAS score change from baseline: 24.22 versus 7.89, P = 0.005).

Chronic nonspecificNA Insufficient
No trial
NA

*Precision in formal grading was applied only to pooled results.

VAS: visual analog scale; RMDQ: Roland-Morris disability scale; NHP: Nottingham health profile; MPQ: McGill pain questionnaire; PDI: pain disability index; SF: short form; NPQ: neck pain questionnaire; SF-PQ: short form pain questionnaire; PRI: pain rating index; PPI: present pain intensity; NA: not applicable; NDI: neck disability index.

External link. Please review our privacy policy.