Table 4

Estimated within-group marginal mean differences for primary and secondary outcome measures.

Outcome	Time	Baseline Mean	Mean ± SE, p-Value
			Chiropractic + PT	Sham + PT
Primary:
FMA	At 4 weeks	40.9	64.1 ± 2.0, <0.001 *	58.0 ± 2.1, <0.001 *
	At 8 weeks		64.3 ± 2.4, <0.001 *	59.8 ± 2.4, <0.001 *
Secondary:
FMA-UE	At 4 weeks	24.1	38.9 ± 1.7, <0.001 *	36.0 ± 1.8, <0.001 *
	At 8 weeks		40.3 ± 2.1, <0.001 *	37.3 ± 2.1, <0.001 *
FMA-LE	At 4 weeks	16.8	25.0 ± 0.8, <0.001 *	22.1 ± 0.9, <0.001 *
	At 8 weeks		24.2 ± 1.0, <0.001 *	22.4 ± 1.0, <0.001 *
SS-QOL	At 4 weeks	122.1	162.5 ± 7.2, <0.001 *	171.7 ± 7.4, <0.001 *
	At 8 weeks		190.6 ± 8.1, <0.001 *	174.0 ± 8.1, <0.001 *
TUG	At 4 weeks	23.7	20.5 ± 1.6, 0.047 *	21.7 ± 1.5, 0.2
	At 8 weeks		21.3 ± 1.8, 0.2	20.4 ± 2.0, 0.1
mRS	At 4 weeks	2.8	2.4 ± 0.2, 0.01 *	2.4 ± 0.2, 0.02 *
	At 8 weeks		2.2 ± 0.2, <0.001 *	2.1 ± 0.2, <0.001 *
5SST	Baseline		MB: 21.3 ± 2.1	MB: 22.7 ± 2.0
	At 4 weeks		17.9 ± 2.1, 0.3	20.8 ± 2.0, 0.5
	At 8 weeks		17.4 ± 2.3, 0.2	17.8 ± 2.6, 0.1

* denotes the null hypothesis is rejected. These marginal means were estimated by the statistical models by holding the baseline scores constant across the two groups, except in the case of 5SST, for which baseline means were also estimated by the respective model. Confidence intervals are presented in the supplementary file. FMA, Fugal-Meyer Assessment; UE, upper extremity; LE, lower extremity; SS-QOL, Stroke Specific Quality of Life; TUG, Time Up and Go; mRS, Modified Rankin Scale; STS, Sit-to-Stand Test.