Table 51Chronic neck pain: effects of nonpharmacological interventions compared with pharmacological treatments

Intervention

Function

Short-Term

Effect Size

Function

Intermediate-Term

Effect Size

Function

Long-Term

Effect Size

Pain

Short-Term

Effect Size

Pain

Intermediate-Term

Effect Size

Pain

Long-Term

Effect Size

Exercise: Versus NSAIDs + Muscle Relaxantsinsufficient evidenceinsufficient evidenceno evidenceinsufficient evidenceinsufficient evidenceno evidence
Exercise (Pilates): Versus Acetaminophen

small

+

no evidenceno evidence

large

+

no evidenceno evidence
Acupuncture: Versus NSAIDsinsufficient evidenceno evidenceno evidenceinsufficient evidenceno evidenceno evidence

Short-Term: 1 to <6 months; Intermediate-Term: ≥6 to <12 months; Long-Term: ≥12 months

Effect Size: none, small, moderate, or large improvement

Strength of Evidence: + = low, ++ = moderate, +++ = high

none = no effect/no statistically significant effect; NSAIDs = nonsteroidal anti-inflammatory drugs; = strength of evidence.

a

and effect size based on totality of evidence from prior report and new trials.

b

New trial of exercise versus pharmacological intervention with short-term followup only. Due to differences in the types of drugs used, the two trials comparing exercise with pharmacological treatments were not amenable to pooling.

From: Discussion

Cover of Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update
Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 227.
Skelly AC, Chou R, Dettori JR, et al.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

External link. Please review our privacy policy.