Systemic Lupus Erythematosus,
Allergic and Inflammatory Diseases,
Migraine, Type II Diabetes, Cardiovascular
and Postmenopausal Issues and
Omega-3 Fatty Acids

This section was compiled by Frank M. Painter, D.C.
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If there are terms in these articles you don't understand, you can get a definition from the Merriam Webster Medical Dictionary.   If you want information about a specific disease, you can access the Merck Manual.   You can also search Pub Med for more abstracts on this, or any other health topic.


Natural Medicine and Nutritional Therapy as an Alternative Treatment
in Systemic Lupus Erythematosus

Alternative Medicine Review 2001 (Oct);   6 (5):   460471 ~ FULL TEXT

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder without a known cure. Conventional medicine typically approaches the disease with a treatment plan that includes the use of corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDS), antimalarial drugs, and chemotherapeutic agents. The results vary and safety is questionable. Conservative treatment methods, such as the use of vitamins, minerals, and fatty acids, have been shown to have an impact on the activity of the disease.

Omega-3 Fatty Acids in the Prevention-management of Cardiovascular Disease
Can J Physiol Pharmacol 1997 (Mar);   75 (3):   234239

Fish oil has been shown to reduce ventricular arrhythmias and to be more beneficial than currently used pharmacologic agents. The dose, duration, and mechanisms involved in the prevention and management of cardiovascular disease following omega-3 fatty acid ingestion or supplementation need to be investigated by double blind controlled clinical trials.

Magnesium Taurate and Fish Oil for Prevention of Migraine
Med Hypotheses 1996 (Dec);   47 (6):   461466

Although many drugs have value for migraine prophylaxis, the two nutritional measures suggested here may have particular merit owing to the versatility of their actions, their safety and lack of side-effects and their long-term favorable impact on vascular health.

Long-term Effects of Eicosapentaenoic Acid (EPA) on Diabetic Peripheral
Neuropathy and Serum Lipids in Patients with Type II Diabetes

J Diabetes Complications 1996 (Sep);   10 (5):   280287

The results of this study suggest that EPA-E has significant beneficial effects on diabetic neuropathy and serum lipids as well as other diabetic complications such as nephropathy and macroangiopathy.

Effects of Interaction of RRR-alpha-tocopheryl Acetate and Fish Oil on
Low-density-lipoprotein Oxidation in Postmenopausal Women with and
without Hormone-replacement Therapy

Am J Clin Nutr 1996 (Feb);   63 (2):   184193

Supplements as low as 100 mg alpha-tocopheryl acetate/d increase the resistance of LDL to oxidation when fish oil supplements are used. HRT and fish oil supplements may independently affect LDL oxidative susceptibility.

Beneficial Effect of Eicosapentaenoic (EPA) and Docosahexaenoic Acids in
the Management of Systemic Lupus Erythematosus (SLE) and its Relationship to
the Cytokine Network

Prostaglandins Leukot Essent Fatty Acids 1994 (Sep);   51 (3):   207213

Oral supplementation of EPA and DHA induced prolonged remission of SLE in 10 consecutive patients without any side-effects. These results suggest that n-3 fatty acids, EPA and DHA, are useful in the management of SLE and possibly, other similar collagen vascular diseases.

Effects of Dietary Fish Oil Lipids on Allergic and Inflammatory Diseases
Allergy Proc 1991 (Sep);   12 (5):   299303

This suggests that EPA has anti-inflammatory potential. Clinical trials in rheumatoid arthritis, psoriasis, atopic dermatitis, and bronchial asthma have shown beneficial effects.

A Fish Oil Diet Rich in Eicosapentaenoic Acid (EPA) Reduces Cyclooxygenase
Metabolites, and Suppresses Lupus in MRL-lpr Mice

J Immunol 1985;   134 (3):   19141919

We suggest that this change in endogenous cyclooxygenase metabolite synthesis directly suppresses immunologic and/or inflammatory mediators of murine lupus.

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