Low basal body temperature and overall sensitivity to cold
Depression. The brain is sensitive to low levels of the thyroid hormone
Weight gain or difficulty in losing weight
Lethargy or fatigue
Dry skin and coarse, brittle hair. Fingernails may become thin and show transverse grooves
Headaches
Menstrual problems such as prolonged and heavy bleeding with a short menstrual cycle.
Infertility may also be a problem
Recurrent infections
Constipation and impaired kidney function
Loss of libido