FROM:
J Pediatr Orthop 2000 (Mar); 20 (2): 251–254
Bone CM, Hsieh GH
Shriners Hospital for Children,
Spokane, Washington, USA
This study set out to determine whether cumulative radiograph exposure of children significantly increases their risk of
radiation-induced carcinogenesis or hereditary defects. Records of children treated for idiopathic scoliosis, hip dysplasia, or leg-length discrepancy between 1980 and 1993 at the Shriners Hospital in Spokane, WA, were retrospectively reviewed. Total radiation and organ dose exposures were calculated using information from individual radiology reports. Surgically
treated idiopathic scoliosis patients had the largest total radiation skin entrance and organ dose exposures. This group's
risks for developing leukemia, breast cancer, or a heritable defect, respectively, were 0.8%, 2.1%, and 3.0% higher than
baseline risks. The other treatment groups had increased carcinogenic risks of <1%. The use of serial radiographs during
the treatment of idiopathic scoliosis, hip dysplasia, and leg-length discrepancy appears relatively safe. The increased
risk of carcinogenesis or hereditary defects in these patients is minimal.