General Grants Funded by FCER

This section was compiled by Frank M. Painter, D.C.
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FCER Funds Multisite Clinical Trial in Australia to Assess
Responsiveness of Asthmatics to Chiropractic Care

FCER has approved funding for a study to be conducted in Australia over the next 18 months. The investigation, "A Multisite Trial: Chiropractic and Asthma with Physiological Markers," is directed by Ray Hayek, Bsc [Hons], MChiro, at Macquarie University in Sydney, Australia

Chiropractic Treatment of Carpal Tunnel Syndrome
and Related Conditions in the Elderly

James R. Hulbert, Ph.D.

Addressing the lack of appropriate chiropractic outcome studies addressed to elderly populations, this proposal is a single-group cohort study which is actually designed to do the work of four pilot projects concerning patients aged 60 years and older with carpal tunnel syndrome [CTS]. The goals of this research are to: [i] determine the feasibility [such as recruitment and treatment effect] of conducting a subsequent randomized clinical trial; [ii] examine the characteristics [such as symptoms and comorbidities] of this group, [iii] develop chiropractic treatment protocols for this condition; and [iv] evaluate the validity and psychometric properties of the proposed outcome measures.

Development and Evaluation of a Reversible Small Animal Model of Chiropractic Subluxation
Charles Henderson, D.C., Ph.D.   &   Gregory Cramer, D.C., Ph.D.

This proposal presents a comprehensive investigation of a small animal model of spinal subluxation consisting of percutaneously attached pins into the spinous process of two adjacent vertebrae. These pins will then be experimentally manipulated, allowing the full external, nontraumatic and reversible control of two key features of the subluxation hypothesis: fixation and malposition. This experimental system, the Rat Transcutaneous Spinous Fixation Model [RTSFM] will be replicated by investigative teams at both Palmer and National Colleges of Chiropractic to assure the practicality of the model in terms of reproducibility, economy and ease of construction.

The Biochemical Profile of Myofascial Trigger Points:
A Clinical Microdialysis Study

Veronica M. Sciotti, Ph.D.

The purpose of the proposed studies is to describe, for the first time, the extracellular milieu of muscle and connective tissue cells using a novel microdialysis sampling technique from the trapezius muscle of human subjects. Clinically diagnosed myofascial trigger points [TrPs] are to be sampled, with unaffected muscle on the opposite side of the subject serving as a control. It is presumed that microdialysis provides an excellent model of microcirculation by means of its ability to selectively collect low-molecular weight metabolites after the insertion of the probe into the fiber of interest.

A Three-Dimensional Model of the Myo-Dural Connection
Gary Hack, D.D.S.

Dr. Hack's recent postulation of a muscle-dural connection responsible for producing headaches, already the subject of a landmark publication in the 1998 Medical and Health Annual of the Encyclopedia Britannica, is to be further developed by the construction of a three-dimensional model in consultation with an engineering company. This model will incorporate the use of 3-D glasses in order to visualize the myo-dural connection that will be created from the Visible Human Project data sets recently made available from the National Institutes of Health.

FCER Funded Study Rates Highest in Literature Review
A critical literature review of 27 randomized clinical trials published between 1966-1995 and addressing neck pain, has been released in the Scandinavian Journal of Rehabilitative Medicine (Kjellman GV, et al. 1999; Vol. 31, pp. 139-152.) An FCER-funded study by P. D. Boline, et al., was included in this review and earned the highest rating of methodological quality of all studies reviewed.

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Updated 8-14-2021

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