CHIROPRACTIC
 
   

Use of Complementary and Integrative Health Therapies and
Chiropractic Care Among Patients Receiving Long-Term
Opioid Therapy in the Department of Veterans Affairs

This section is compiled by Frank M. Painter, D.C.
Send all comments or additions to:
   Frankp@chiro.org
 
   

FROM:   J Integr Complement Med 2025 (Nov 14) [EPUB] ~ FULL TEXT

  OPEN ACCESS   


Anne C Black • Steven B Zeliadt • Robert D Kerns
Jamie H Douglas • Erica A Abel • Haseena Rajeevan, et al.

VA Connecticut Healthcare System,
West Haven, CT, USA.


Background:   Use of complementary and integrative health (CIH) therapies has increased over the past two decades. Accumulating evidence supports the effectiveness of CIH therapies for a range of health outcomes and an association between CIH therapy use and reduced use of opioid therapy.

Objective:   To describe differences in the use of evidence-based CIH therapies among individuals with chronic pain on long-term opioid therapy (LTOT) by sociodemographic and clinical characteristics.

Design:   This was an observational study using a national retrospective cohort of patients developed from Veterans Affairs (VA) electronic health record data.

Sample:   The sample comprised 281,903 patients receiving LTOT upon cohort entry between July 1, 2017, and December 31, 2021, with a health care encounter in one of 54 VA medical centers.

Main Measures:   CIH therapy use was defined as chart-documented use of any of eight priority CIH therapies or chiropractic care in the year prior to cohort entry. LTOT was defined as having a prescribed opioid analgesic for ≥90 consecutive days, allowing ≤30 days between fills. Sociodemographic and clinical characteristic variables were assessed as covariates of CIH therapy use.

Key Results:   Among the full cohort, the CIH therapy use rate was 9.5%. Use increased with each cohort entry year relative to 2017. In a multivariable model, variables associated with greater odds of CIH therapy use included being female, having a musculoskeletal pain condition, obesity, opioid use disorder, anxiety, depression, post-traumatic stress disorder, and receiving services in a flagship site. Lower odds of use were associated with being older, unmarried, prescribed higher opioid doses, smoking, and rural residence.

Conclusions:   CIH therapy use has increased over time, consistent with national trends; however, differential patterns of exposure suggest the need to explore pathways to use. These may elucidate opportunities to broaden access to these evidence-based therapies for patients with chronic pain.

Keywords:   CIH; chronic pain; opioid therapy; veterans; whole health.



From the Full-Text Article:




































Additional files

Additional file 1: Appendix A. The chiropractic profession a scoping review (DOCX 13 kb)


















References:

  1. Nahin RL, Rhee A, Stussman B.
    Use of complementary health approaches overall and for
    pain management by US adults.
    JAMA 2024;331(7):613–615;

  2. National Center for Complementary and Integrative Health.
    NCCIH strategic plan FY 2021–2025:
    Mapping the pathway to research on whole person health.
    Bethesda, MD: National Institute of Health; 2021.
    Available from: https://www.nccih.nih.gov/about/nccih-
    strategic-plan-2021-2025 [Last accessed: September 26, 2025].

  3. Qaseem A, Wilt TJ, McLean RM, et al.;
    Clinical Guidelines Committee of the American College of Physicians.
    Noninvasive Treatments for Acute, Subacute, and Chronic
    Low Back Pain: A Clinical Practice Guideline
    From the American College of Physicians

    Annals of Internal Medicine 2017 (Apr 4); 166 (7): 514–530

  4. Department of Veterans Affairs.
    VA/DOD Clinical Practice Guideline For The Use Of
    Opioids in The Management Of Chronic Pain

    Version 4.0 – 2022

  5. U.S. Department of Health and Human Services. (2019, May).
    Pain Management Best Practices Inter-Agency Task Force Report:
    Updates, Gaps, Inconsistencies, and Recommendations.
    Retrieved from U. S. Department of Health and Human Services.
    Available from: https://www.hhs.gov/sites/default/files/pmtf-
    final-report-2019-05-23.pdf [Last accessed: September 26, 2025].

  6. Department of Veterans Affairs.
    Management of posttraumatic stress disorder and acute stress disorder
    work group. Department of Veterans Affairs online; 2023.
    Available from: https://www.healthquality.va.gov/guidelines/MH/ptsd/
    VA-DoD-CPG-PTSD-Full-CPG-Edited-111624-V5-81825.pdf
    [Last accessed: September 26, 2025].

  7. Edinger JD, Arnedt JT, Bertisch SM, et al.
    Behavioral and psychological treatments for chronic insomnia disorder
    in adults: An American Academy of Sleep Medicine
    clinical practice guideline.
    J Clin Sleep Med 2021;17(2):255–262;

  8. Greenlee H, DuPont-Reyes MJ, Balneaves LG, et al.
    Clinical practice guidelines on the evidence-based use of integrative
    therapies during and after breast cancer treatment.
    CA Cancer J Clin 2017;67(3):194–232;

  9. Tick H, Nielsen A, Pelletier KR, et al.; Pain Task Force of the
    Academic Consortium for Integrative Medicine and Health.
    Evidence-based nonpharmacologic strategies for
    comprehensive pain care: The consortium
    pain task force white paper.
    Explore (NY) 2018;14(3):177–211;

  10. Coffee Z, Cheng K, Slebodnik M, et al.
    The impact of nonpharmacological interventions on opioid use
    for chronic noncancer pain: A scoping review.
    Int J Environ Res Public Health 2024;21(6):794;

  11. Pangarkar SS, Kang DG, Sandbrink F, et al.
    VA/DoD clinical practice guideline:
    Diagnosis and treatment of low back pain.
    J Gen Intern Med 2019;34(11):2620–2629;

  12. Frank JW, Carey E, Nolan C, et al.
    Increased nonopioid chronic pain treatment in the
    Veterans Health Administration, 2010–2016.
    Pain Med 2019;20(5):869–877;

  13. Pritchard KT, Baillargeon J, Lee W-C, et al.
    Trends in the use of opioids vs. nonpharmacologic treatments
    in adults with pain, 2011-2019.
    JAMA Netw Open 2022;5(11):e2240612;

  14. Gaudet T, Kligler B.
    Whole Health in the Whole System of the Veterans Administration:
    We Know We Have Reached This Future State?

    J Altern Complement Med 2019 (Mar); 25 (S1): S7–S11

  15. Bokhour BG, Haun JN, Hyde J, et al.
    Transforming the Veterans Affairs to a whole health system
    of care: Time for action and research.
    Med Care 2020;58(4):295–300;

  16. Kligler B, Bair MJ, Banerjea R, et al.
    Clinical Policy Recommendations from the VHA State-of-the-Art
    Conference on Non-Pharmacological Approaches
    to Chronic Musculoskeletal Pain

    J Gen Intern Med 2018 (May); 33 (Suppl 1): 16–23

  17. Kerns RD, Krebs EE, Atkins D.
    Making integrated multimodal pain care a reality:
    a path forward.
    Springer; 2018. pp. 1–3;

  18. Department of Veterans Affairs. VHA Directive 1137.
    Provision of complementary and integrative health.
    Available from: https://www.va.gov/WHOLEHEALTH/professional-
    resources/clinician-tools/cih.asp
    [Last accessed: September 26, 2025].

  19. Whitehead AM, Kligler B.
    Innovations in care: Complementary and integrative health in
    the Veterans Health Administration whole health system.
    Med Care 2020;58(Suppl 2) 9S:S78–S79;

  20. Chou R, Deyo R, Friedly J, et al.
    Nonpharmacologic Therapies for Low Back Pain:
    A Systematic Review for an American College
    of Physicians Clinical Practice Guideline

    Annals of Internal Medicine 2017 (Apr 4); 166 (7): 493–505

  21. Dyer NL, Surdam J, Dusek JA.
    A systematic review of practiced-based research of complementary
    and integrative health therapies as provided for pain
    management in clinical settings: Recommendations
    for the future and a call to action.
    Pain Med 2022;23(1):189–210;

  22. Gantt CJ, Donovan N, Khung M.
    Veterans Affairs’ whole health system of care for
    transitioning service members and Veterans.
    Mil Med 2023;188(Suppl 5):28–32;

  23. Resnick A, Zeliadt SB, Ganz DA, et al.
    Changes in use of complementary and integrative health
    therapies at the Veterans Affairs: Findings from
    a whole health system pilot program.
    J Integr Complement Med 2023;29(12):805–812;

  24. Taylor SL, Gelman HM, DeFaccio R, et al.
    We Built It, But Did They Come: Veterans' Use of VA
    Healthcare System-Provided Complementary
    and Integrative Health Approaches

    J Gen Intern Med 2022 (Nov 30); 38 (4): 905–912

  25. Zeliadt S, DeFaccio R, Resnick A, et al.
    Compendium on the use of core whole health services, complementary
    and integrative health therapies, and chiropractic care at the
    VA. Volume 2: transitions in care due to the COVID-19 pandemic,
    2017–2020. 2023.

  26. Han L, Goulet JL, Skanderson M, et al.
    Impact of complementary health approaches on opioid prescriptions
    among Veterans with musculoskeletal disorders—
    A retrospective cohort study.
    J Pain 2025;26:104695;

  27. Black AC, Zeliadt SB, Kerns RD, et al.
    Association between exposure to complementary and integrative
    therapies and opioid analgesic daily dose among veterans
    on long-term opioid therapy.
    Clin J Pain 2022;38(6):405–409;

  28. Zeliadt SB, Douglas JH, Gelman H, et al.
    Effectiveness of a whole health model of care emphasizing
    complementary and integrative health on reducing
    opioid use among veterans with chronic pain.
    BMC Health Serv Res 2022;22(1):1053;

  29. Herman PM, Yuan AH, Cefalu MS, et al.
    The use of complementary and integrative health approaches
    for chronic musculoskeletal pain in younger US veterans:
    An economic evaluation.
    PLoS One 2019;14(6):e0217831;

  30. Edelman EJ, Gordon K, Becker WC, et al.
    Receipt of opioid analgesics by HIV-infected and uninfected patients.
    J Gen Intern Med 2013;28(1):82–90;

  31. Department of Veterans Affairs Office of Productivity Efficiency,
    and Staffing. VHA facility complexity model fact sheet.
    Available from: https://reports.vssc.med.va.gov/ReportServer/
    Pages/ReportViewer.aspx?/OPES/FacilityComplexity/FacilityComplex
    History&rs:Command=Render [Last accessed: September 26, 2025].

  32. Lund BC, Ohl ME, Hadlandsmyth K, Mosher HJ.
    Regional and rural–urban variation in opioid prescribing
    in the Veterans Health Administration.
    Mil Med 2019;184(11–12):894–900;

  33. Department of Veterans Affairs Office of Rural Health.
    How to define rurality fact sheet.
    Available from: https://www.ruralhealth.va.gov/docs/
    ORH_RuralityFactSheet_508.pdf

  34. US Department of Agriculture Economic Research Service.
    Rural-urban community area codes. Available from:
    https://www.ers.usda.gov/data-products/rural-urban-commuting-
    area-codes [Last accessed: September 26, 2025].

  35. Goulet JL, Kerns RD, Bair M, et al.
    The musculoskeletal diagnosis cohort: Examining pain
    and pain care among Veterans.
    Pain 2016;157(8):1696–1703;

  36. Rodgers-Melnick SN, Trager RJ, Love TE, Dusek JA.
    Engagement in integrative and nonpharmacologic pain management
    modalities among adults with chronic pain: Analysis of
    the 2019 National Health Interview Survey.
    J Pain Res 2024;17:253–264;

  37. Reed DE, Bokhour BG, Gaj L, et al.
    Whole Health use and interest across veterans with co-occurring
    chronic pain and PTSD: An examination of the 18 VA
    medical center flagship sites.
    Glob Adv Health Med 2022;11:21649561211065374;

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