Paracetamol and paracetamol-weak
opioid compounds prescribed at regular intervals effectively reduce acute
low back pain. Comparisons of effectiveness to NSAIDs are inconsistent.
NSAIDs prescribed at regular
intervals effectively reduce simple backache.
Different NSAIDs are equally
effective for the reduction of simple backache.
NSAIDs can have serious
adverse effects particularly at high doses and in the elderly. Ibuprofen,
followed by diclofenac, has the lowest risk of gastrointestinal
complications.
NSAIDs are less effective for
the reduction of nerve root pain.
Paracetamol-weak opioid
compounds may be effective alternatives when paracetamol or NSAIDs alone
do not give adequate pain control. Adverse effects include constipation
and drowsiness.
de Craen et al 1996. Henry et al 1996, Koes
et al 1996a, van Tulder et al 1996a
